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博士生詹红菊的论文在JOURNAL OF LUMINESCENCE刊出
发布时间:2013-01-17 15:40:40     发布者:admin     浏览次数:

标题:Multi-spectroscopic techniques to evaluate the toxicity of alloyed CdSeS quantum dots

作者:Zhan, HJ(Zhan, Hong-Ju); Zhou, PJ(Zhou, Pei-Jiang); Ding, L(Ding, Ling); He, ZY(He, Zhen-Yu); Ma, R(Ma, Rong)

来源出版物:JOURNAL OF LUMINESCENCE卷:132 期:10 页:2769-2774 出版年:OCT 2012

摘要:Alloyed CdSeS quantum dots (QDs) were successfully synthesized in aqueous phase using microwave irradiation. UV-vis spectroscopy, fluorescence spectroscopy, transmission electron microscopy (TEM) and X-ray diffraction (XRD) techniques proved that the prepared alloyed QDs are composed of a CdSe-rich core and thick CdS shell with homogeneous size distributions. In order to study its biological toxicity, multi-spectroscopic techniques were adopted to investigate their conjugation with BSA. Fluorescence quenching methods indicated the prepared CdSeS QDs strongly quenched the fluorescence of BSA due to the formation of non-fluorescence ground-state complex. UV-vis absorbance spectra, synchronous fluorescence spectra and CD spectra further confirmed the alloyed CdSeS QDs binded with BSA and destroyed their hydrogen bonding networks, which induced the conformation changes of this macromolecule.

文献类型:Article

语种:English

作者关键词:Alloyed quantum dots, Microwave synthesis, Static quenching, Bovine serum albumin

扩展关键词:BOVINE SERUM-ALBUMIN; FLUORESCENCE; NANOPARTICLES; HEMOGLOBIN; PROTEINS; BINDING; CELLS; SIZE; BSA

通讯作者地址:Zhou, PJ (通讯作者),Wuhan Univ, Sch Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Peoples R China.

地址:

[Zhan, Hong-Ju; Zhou, Pei-Jiang; Ding, Ling; He, Zhen-Yu; Ma, Rong] Wuhan Univ, Sch Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Peoples R China

[Zhan, Hong-Ju] Jingchu Univ Technol, Jingmen 448000, Peoples RChina

[Ding, Ling]Wuhan Univ Sci & Technol, Coll Chem Engn & Technol, Wuhan 430081, Peoples R China

[He, Zhen-Yu]Wuhan Ctr Dis Prevent & Control, Wuhan 430022, Peoples R China

电子邮件地址2010102050026@whu.edu.cn;zhoupj@whu.edu.cn" data-ke-src=" mailto:zhoupj@whu.edu.cn?>zhoupj@whu.edu.cn" data-ke-src=" mailto:zhoupj@whu.edu.cn?>zhoupj@whu.edu.cn"zhoupj@whu.edu.cn

学科类别:Optics

ISSN:0022-2313

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