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肖玲、博士生刘丽等的论文在JOURNAL OF NANOPARTICLE RESEARCH刊出
发布时间:2013-06-17 09:09:11     发布者:yz     浏览次数:

标题:Studies on interaction and illumination damage of CS-Fe3O4@ZnS:Mn to bovine serum albumin作者:Liu, Li; Xiao, Ling;Zhu, Hua-Yue; Shi, Xiao-Wen

来源出版物:JOURNAL OF NANOPARTICLE RESEARCH 卷:15 期:1 文献编号:1394 DOI:10.1007/s11051-012-1394-3 出版年:JAN 2013

摘要:In this study, the interaction of chitosan (CS) coated CS-Fe3O4@ZnS:Mn magnetic-fluorescent nanoparticles (MFNPs) with bovine serum albumin (BSA) was studied by means of ultraviolet-visible and fluorescence spectra; evidences for the damage of BSA molecule in the presence of CS-Fe3O4@ZnS:Mn MFNPs under UV illumination were also obtained. The results show that the dominating fluorescence quenching mechanism of CS-Fe3O4@ZnS:Mn MFNPs with BSA belongs to static quenching. Fluorescence resonance energy transfer (FRET) occurred from BSA to CS-Fe3O4@ZnS:Mn MFNPs. The thermodynamic parameters indicated that electrostatic interaction play major roles in CS-Fe3O4@ZnS:Mn-BSA, while binding processes exist spontaneously. In addition, the damage of CS-Fe3O4@ZnS: Mn MFNPs to BSA molecule under UV illumination was studied under various experimental parameters. It was proved that: the damage of BSA is prone to happen in the presence of CS-Fe3O4@ZnS:Mn MFNPs under UV illumination, there is synergic effect of oxygen and UV illumination on the damage of BSA, and the fluorescence quenching of BSA by CS-Fe3O4@ZnS:Mn MFNPs under UV illumination is mainly a result of a photo-induced free radical procedure.

入藏号:WOS:000318550000079

文献类型:Article

语种:English

作者关键词:Magnetic-fluorescent nanoparticles, Bovine serum albumin (BSA), Interaction, UV illumination, Reactive oxygen species (ROS)

扩展关键词:SEMICONDUCTOR QUANTUM DOTS; VISIBLE-LIGHT IRRADIATION; RESONANCE ENERGY-TRANSFER; SPECTROSCOPIC TECHNIQUES; MAGNETIC NANOPARTICLES; ULTRASONIC IRRADIATION; AQUEOUS-MEDIA; FLUORESCENCE; PROTEIN; NANOCOMPOSITES

通讯作者地址:Xiao, Ling; Luojia Mt Wuchang, Wuhan 430072, Hubei, Peoples R China.

电子邮件地址:liuli520666@sohu.com; xiaoling9119@yahoo.cn; zhuhuayue@126.com; shixwwhu@163.com

地址:

[Liu, Li; Xiao, Ling; Zhu, Hua-Yue; Shi, Xiao-Wen] Wuhan Univ, Coll Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430072, Peoples R China.

[Liu, Li; Xiao, Ling; Zhu, Hua-Yue; Shi, Xiao-Wen] Luojia Mt Wuchang, Wuhan*430072*,Hubei, Peoples RChina.

研究方向:Chemistry; Science & Technology - Other Topics; Materials Science

ISSN:1388-0764

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