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博士生詹红菊的论文在EUROPEAN JOURNAL OF INORGANIC CHEMISTRY刊出
发布时间:2013-01-17 16:07:26     发布者:admin     浏览次数:

标题:Microwave-Assisted Aqueous Synthesis of Small-Sized, Highly Luminescent CdSeS/ZnS Core/Shell Quantum Dots for Live Cell Imaging

作者:Zhan, HJ(Zhan, Hong-Ju); Zhou, PJ(Zhou, Pei-Jiang); He, ZY(He, Zhen-Yu); Tian, Y(Tian, Yuan)

来源出版物:EUROPEAN JOURNAL OF INORGANIC CHEMISTRY 期:15 页: 出版年:2487-2493

摘要:This study develops a reliable aqueous-phase method for the synthesis of CdSeS/ZnS core/shell QDs employing microwave irradiation technique. Firstly, CdSeS core QDs were produced by heating a precursor solution containing Cd2+, 3-mercaptopropionic acid (MPA) and Na2SeSO3 at 130 degrees C for 30 min. After purification through centrifugation, the CdSeS core QDs were successfully capped with a ZnS shell through heating a capping solution containing Zn2+, S2 and MPA at 100 degrees C for 1 h. Both the core/shell QDs and core QDs were characterised by X-ray powder diffraction, transmission electron microscopy and X-ray photoelectron spectroscopy, and the epitaxial growth of a ZnS shell on the surface of CdSeS QDs was confirmed. The prepared CdSeS/ZnS core/shell QDs showed significantly enhanced luminescence and photostability than that of CdSeS core QDs. Finally, the CdSeS/ZnS core/shell QDs were applied to image live Hela cells. The pilot experiments showed that the cells were successfully stained and exhibited bright green fluorescence. The small size QDs were localised predominantly in the nuclear compartment of Hela cells with negligible cytotoxicity, even at a concentration of 300 mu g?mL-1 after 24 h incubation. Our results suggest that the new core/shell QDs could be highly biocompatible and have wide applications in biolabelling and imaging.

文献类型:Article

语种:English

作者关键词:Synthetic methods, Microwave-assisted synthesis, Quantum dots, -Imaging agents, Cadmium, Zinc, -Photochemistry

扩展关键词:ORE-SHELL NANOCRYSTALS; ONE-POT SYNTHESIS; MULTISHELL NANOCRYSTALS;CDTE NANOCRYSTALS;CDSE NANOCRYSTALS;EPITAXIAL-GROWTH;PHOTOLUMINESCENCE;BIOCOMPATIBILITY; PHOTOSTABILITY; NANOPARTICLES

通讯作者地址:Zhou, PJ (通讯作者),Wuhan Univ, Sch Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Peoples R China

地址:

[Zhan, Hong-Ju; Zhou, Pei-Jiang; He, Zhen-Yu; Tian, Yuan]Wuhan Univ, Sch Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Peoples R China

[Zhan, Hong-Ju]Jingchu Univ Technol, Jingmen 448000, Peoples RChina

[He, Zhen-Yu]Wuhan Ctr Dis Prevent & Control, Wuhan 430022, Peoples R China

电子邮件地址:zhoupj@whu.edu.cn

学科类别:Chemistry

ISSN:1434-1948

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