标题：Electrical Signal Guided Ibuprofen Release from Electrodeposited Chitosan Hydrogel作者：Liu, Youyu; Yan, Kun; Jiang, Guoxia; Xiong, Yuan; Du, Yumin; Shi,Xiaowen

来源出版物：INTERNATIONAL JOURNAL OF POLYMER SCIENCE 文献号：736898 DOI：10.1155/2014/736898 出版年：2014

摘要：Electrical signal guided drug release from conductive surface provides a simple and straightforward way for advanced drug delivery. In this study, we investigated the ibuprofen release from electrodeposited chitosan hydrogel by applying electrical signals. Specifically, chitosan hydrogel was electrodeposited on titanium plate and used as a matrix for ibuprofen load and release. The release of ibuprofen from the chitosan hydrogel on titanium plate was pH sensitive. By applying a positive or negative electrical potential, the release rate of ibuprofen from the electrodeposited chitosan can be facilely controlled. Thus, coupling chitosan electrodeposition and electrical signal control spurs new possibilities for biopolymeric coating and drug elution on conductive implants.

入藏号：WOS:000342949600001

文献类型：Article

语种：English

扩展关键词：CONTROLLED DRUG-RELEASE; BIOPOLYMERIC HYDROGEL; DELIVERY; NANOPARTICLES; PREDNISOLONE; CONJUGATE; FIBERS; CANCER; CELLS

通讯作者地址：Shi,Xiaowen; Wuhan Univ, Hubei Biomass Resource Chem & Environm Biotechnol, Sch Resource & Environm Sci, Wuhan 430079, Peoples R China.

电子邮件地址：shixwwhu@163.com

地址：

[Liu, Youyu; Yan, Kun; Jiang, Guoxia; Xiong, Yuan; Du, Yumin; Shi,Xiaowen]Wuhan Univ, Hubei Biomass Resource Chem & Environm Biotechnol, Sch Resource & Environm Sci, Wuhan 430079, Peoples R China.

研究方向：Polymer Science

ISSN：1687-9422