标题: Catechol-Based Capacitor for Redox-Linked Bioelectronics

作者: Wu, S (Wu, Si); Kim, E (Kim, Eunkyoung); Li, JY (Li, Jinyang); Bentley, WE (Bentley, William E.); Shi, XW (Shi, Xiao-Wen); Payne, GF (Payne, Gregory F.)

来源出版物: ACS APPLIED ELECTRONIC MATERIALS  卷: 1  期: 8  页: 1337-1347  DOI: 10.1021/acsaelm.9b00272  出版年: AUG 2019  

摘要: A common bioelectronics goal is to enable communication between biology and electronics, and success is critically dependent on the communication modality. When a biorelevant modality aligns with instrumentation capabilities, remarkable successes have been observed (e.g., electrodes provide a powerful tool to observe and actuate biology through its ion-based electrical modality). Emerging biological research demonstrates that redox is another biologically relevant modality, and recent research has shown that advanced electrochemical methods enable biodevice communication through this redox modality. Here, we briefly summarize the biological relevance of this redox modality and the use of redox mediators to enable access to this modality through electrochemical measurements. Next, we describe the fabrication of a catechol-chitosan redox capacitor that is redox-active but nonconducting and thus offers a unique set of molecular electronic properties that enhance access to redox-based information. Finally, we cite several recent studies that demonstrate the broad potential for this capacitor to access redox-based biological information. In summary, we envision the redox capacitor will become a vital component in the integrated circuitry of redox-linked bioelectronics.

入藏号: WOS:000496315000001

语言: English

文献类型: Article

作者关键词: catechol; chitosan; mediators; redox biology; redox capacitor

地址: [Wu, Si; Shi, Xiao-Wen] Wuhan Univ, Sch Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Hubei, Peoples R China.

[Wu, Si; Kim, Eunkyoung; Li, Jinyang; Bentley, William E.; Payne, Gregory F.] Univ Maryland, Inst Biosci & Biotechnol Res, College Pk, MD 20742 USA.

[Li, Jinyang; Bentley, William E.] Univ Maryland, Fischell Dept Bioengn & Res, College Pk, MD 20742 USA.

通讯作者地址: Shi, XW (通讯作者)，Wuhan Univ, Sch Resource & Environm Sci, Hubei Biomass Resource Chem & Environm Biotechnol, Wuhan 430079, Hubei, Peoples R China.

Payne, GF (通讯作者)，Univ Maryland, Inst Biosci & Biotechnol Res, College Pk, MD 20742 USA.

电子邮件地址: shixw@whu.edu.cn; gpayne@umd.edu