标题：Antimicrobial activity and cytotoxicity of nanofibrous mats immobilized with polysaccharides-rectorite based nanogels作者：Zhang, Jianwei; Li, Xueyong; Tian, Jing; Lu, Yuan; Shi, Xiaowen; Zhan,

Yingfei; Du, Yumin; Liu, Huan; Deng, Hongbing

来源出版物：COLLOIDS AND SURFACES B-BIOINTERFACES 卷：133 页：370-377 DOI：10.1016/j.colsurfb.2015.04.051 出版年：SEP 1 2015

摘要：Rectorite (REC)-encapsulated lysozyme(LY)-alginate(ALG)nanogels (NGs) were prepared by adding ALG-REC composites suspensions into LY solutions at the mass ratio of 1:2. The morphology of the NGs and the NGs-assembled nanofibrous mats were studied by transmission electron microscope and field emission scanning electron microscopy, respectively. The composition of NGs-immobilized nanofibrous mats was detected by X-ray photoelectron spectroscopy. The NGs-assembled nanofibrous mats with the addition of REC could enhance the inhibition against Escherichia coli and Staphylococcus aureus. Additionally, NGs-coated mats reduced the toxicity of cellulose mats on mouse lung fibroblasts using MIT assay. Besides, the addition of REC in the NGs improved the cell compatibility of NGs-assembled nanofibrous mats.

入藏号：WOS:000359172600045

文献类型：Article

语种：English

作者关键词：Nanogels, Rectorite, Antibacterial, Cytotoxicity

扩展关键词：METAL NANOPARTICLES; CELLULOSE-ACETATE; LYSOZYME; SCAFFOLDS; CHITOSAN; FILMS; NANOCOMPOSITE; COMPOSITES; FIBERS

通讯作者地址：Liu, Huan; Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China.

电子邮件地址：liuhuan@wh.iov.cn; hbdeng@whu.edu.cn

地址：

[Zhang, Jianwei; Shi, Xiaowen; Zhan, Yingfei; Du, Yumin; Deng, Hongbing] Wuhan Univ, Dept Environm Sci, Hubei Key Lab Biomass Resource & Environm Biotech, Sch Resource & Environm Sci, Wuhan 430079, Peoples R China.

[Li, Xueyong] Fourth Mil Med Univ, Tangdu Hosp, Dept Plast Surg, Xian 710038, Peoples R China.

[Tian, Jing] Huazhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Peoples R China.

[Lu, Yuan] Guangxi Univ, Sch Chem & Chem Engn, Nanning 530004, Peoples R China.

[Liu, Huan] Chinese Acad Sci, Wuhan Inst Virol, State Key Lab Virol, Wuhan 430071, Peoples R China.

研究方向：Biophysics; Chemistry; Materials Science

ISSN：0927-7765

eISSN：1873-4367

影响因子（2014）：4.152